Sandeep urandur

Sandeep urandur

About

Detail

Formulation Scientist | LNP & Drug Product Development | Small Molecules & Biologics | Analytical Method Development | Ph.D. in Pharmaceutics
Pennsylvania, United States
Contact Sandeep regarding: 
work
Full-time jobs

Timeline

work
Job
school
Education
flag
Award
auto_stories
Publication

Résumé

Jobs verified_user 0% verified
  • University of Pittsburgh
    Postdoctoral Associate
    University of Pittsburgh
    Mar 2023 - Current (3 years 5 months)
    Project Details: Leading advanced drug delivery system development for clinical applications *Developed hybrid LNP-EV delivery systems for extended-release applications using QbD principles *Led pilot scale-up manufacturing coordination for small molecules and monoclonal antibodies *Managed CMO technology transfer for scale-up batch production, optimizing formulation parameters *Established discriminatory analytical methods including stability-indicating assays for both small molecules and biologics *Applied PAT tools (NIR spectroscopy) for real-time process monitoring and blend uniformity assessment *Secured independent research funding as Principal Investigator (MWRIF Pilot Grant 2024) *Supported pre-IND documentation and regulatory filin
  • University of Delaware
    Postdoctoral Researcher
    University of Delaware
    Mar 2022 - Feb 2023 (1 year)
    Project details: Development of thermo-responsive peptide-based nano materials coated coacervates for building a synthetic cell model as well as a delivery system for small and macromolecules. Key duties: • Synthesis of peptides by using microwave assisted method and its purification by preparative HPLC technique. • Formulation and development of peptide based nanoparticles; conjugation of fluorescent dyes to peptides through click chemistry or by other conjugation techniques. • Preparation of polypeptide coacervates by using liquid-liquid phase separation method. • Physicochemical characterization of peptide nanoparticles using techniques like DLS, CD, TEM, SEM, confocal microscopy, FTIR and Mass Spec. • To write research, review articles,
  • Bristol Myers Squibb
    Research Investigator
    Bristol Myers Squibb
    May 2020 - Feb 2022 (1 year 10 months)
    The role involved the planning, coordination, and execution of pre-formulation studies and product development for small molecules from initial development stage to Phase II clinical stage. Key Responsibilities • To conduct preformulation studies on potential new drug candidates with the purpose to interpret physicochemical and biopharmaceutical properties relevant to drug candidates. • To design strategically and guide the development of formulations suitable for use in drug discovery, pharmacology studies, PK studies and initial toxicology studies; screening of suitable vehicles and related analysis using UPLC, PXRD as per the study requirement. • To carry out in-vitro biopharmaceutic risk assessment studies in early drug discovery stages
  • C
    Research Fellow
    Central Drug Research Institute Lucknow
    Jan 2015 - May 2020 (5 years 5 months)
    • Hands-on experience with Liposomes or other nanoparticle drug delivery systems such as Hexosomes, Crystallsomes, Polymeric & Lipidic nanoparticles, Lyophilized injectables, and Transdermal patches. • Successfully licensed the technology based on novel self-nanoemulsifying oral formulation strategy for CDRI therapeutic candidate. • Employed various characterization techniques, in-vitro and in-vivo experiments for the screening of candidate formulation. • Designed various formulations trials, dissolution studies, stability studies of solid and liquid dosage forms. • Experience of using QbD design for Process and Formulation development of injectable and oral formulations. • Contributed to departmental quality documentation including SOP’s,
  • K
    Project Trainee
    Karnataka Antibiotics Pharmaceuticals Limited Peenya Bangalore
    Dec 2012 - May 2013 (6 months)
    • Formulation development and optimization of chewable tablets, matrix tablets and novel drug delivery systems especially nano formulations like SLNs, Liposomes. • Bio-analytical method development and validation using UV-Vis and HPLC. • Preclinical Pharmacokinetic evaluation for the developed formulations in-vitro and in-vivo.
Education verified_user 0% verified
  • C
    Doctor of Philosophy - PhD, Pharmaceutical Sciences
    CSIRCentral Drug Research Institute
    Jan 2015 - Dec 2020 (6 years)
    • Senior Research Fellowship (SRF) by Council of Scientific and Industrial Research (CSIR), New Delhi, India. 2017. • Junior Research Fellowship (JRF) by Council of Scientific and Industrial Research (CSIR), New Delhi, India. 2015.
  • Rajiv Gandhi University of Health Sciences
    Bachelor's degree and Master's degree, Pharmacy
    Rajiv Gandhi University of Health Sciences
    Jan 2007 - Dec 2013 (7 years)
    • 2013: M-pharmacy from department of pharmaceutics, Vivekananda College of Pharmacy, Rajiv Gandhi University of Health Sciences, Karnataka, Bangalore. (scored-78%; Distinction) • 2011: B-pharmacy from St. Johns college of pharmacy, Rajiv Gandhi University of Health Sciences, Karnataka, Bangalore. (Scored-71%)
Awards verified_user 0% verified
  • C
    CDRI director’s special incentive award for excellence in research 2019
    CSIRCentral Drug Research Institute
    Mar 2021
  • R
    Recieved Technology of the Year Award 2020
    Feb 2020
    The Technoloy of the Year Award of Rupees Three lakh was conferred to our research groups for the successful technology transfer of “Standardized fraction enriched with N-012-0001 for the management of Benign Prostatic Hyperplasia (BPH)”.
  • D
    Awarded Tata Innovation Fellowship 2018-19 to our group by DBT Govt. of India
    DBT Govt of India
    Jan 2019
    Awarded Tata Innovation Fellowship 2018-19 to our group by DBT Govt. of India for our contribution in the area of translational research based on controlled and targeted drug delivery technologies
  • C
    Recipient of Dr. JM Khanna memorial early career achievement award- 2019
    CSIRCentral Drug Research Institute Lucknow India
    Jan 2019
  • R
    Best poster presentation award at international conference on Cell Death in Cancer and Toxicology
    Roswell Park Comprehensive Cancer Centre Buffalo USA
    Jan 2018
    Best poster presentation award at international conference on Cell Death in Cancer and Toxicology 2018 (CDCT, February 20–22, 2018) held at CSIR-Indian Institute of Toxicology Research (IITR), Lucknow, India organized by (IITR Lucknow, India), Roswell Park Comprehensive Cancer Centre, Buffalo, USA) and International Cell Death Society, USA
  • C
    Recipient of CSIR (Council of Scientific and Industrial Research, New-Delhi, India) Grant 2018
    Council of Scientific and Industrial Research CSIR New Delhi India
    Jan 2018
    Recipient of CSIR (Council of Scientific and Industrial Research, New-Delhi, India) Grant to attend 10th Microencapsulation Training School-Cell & Drug Encapsulation, organized by Bioencapsulation Research Group, held in Trondheim, Norway during September 18-21, 2018
  • S
    Senior Research Fellowship (SRF) by Council of Scientific and Industrial Research (CSIR), New Delhi, India. 2017
    Jan 2017
  • C
    Recipient of director’s special incentive award 2016
    CSIRCentral Drug Research Institute Lucknow India
    Jan 2016
    Recipient of director’s special incentive award 2016 for excellence in research in 2016 for publishing in highest impact factor journal
  • C
    Junior Research Fellowship (JRF) by Council of Scientific and Industrial Research (CSIR), New Delhi, India. 2015
    Council of Scientific and Industrial Research CSIR New Delhi India
    Jan 2015
  • C
    Qualified in CSIR-NET June 2014, All India Rank-50
    Council of Scientific and Industrial Research CSIR New Delhi India
    Jan 2014
  • U
    Graduate Aptitude Test in Engineering (GATE) fellowship by University Grants Commission (UGC), New Delhi.2011
    University Grants Commission UGC New Delhi
    Jan 2011
  • B
    Best poster presentation award on “AIDS & PREGNANCY” held at St. Johns Pharmacy College
    Jan 2011
Publications verified_user 0% verified
  • B
    Development of putrescine anchored nano-crystalsomes bearing doxorubicin and oleanolic acid: deciphering their role in i
    Biomaterials Science
    Jan 2021
  • A
    Theranostic lyotropic liquid crystalline nanostructures for selective breast cancer imaging and therapy
    Acta Biomaterilia
    Jan 2020
  • B
    Targeted co-delivery of the aldose reductase inhibitor epalrestat and chemotherapeutic doxorubicin via a redox-sensitive
    Biomaterials ScienceRoyal Society of Chemistry
    Jan 2019
  • B
    Multifunctional hybrid nanoconstructs facilitates intracellular localization of Doxorubicin and Genistein to enhance apo
    Biomaterials ScienceRoyal Society of Chemistry
    Jan 2019
  • C
    Remediation of hormone refractory breast cancer via co-loaded phytoliposomes
    CANCER MEDICINEWILEY
    Jan 2018
  • C
    Boosting combination chemotherapeutic efficacy of Metformin and Topotecan using ion trapping assisted ratiometric delive
    CANCER MEDICINEWILEY
    Jan 2018
  • T
    Nonlamellar liquid crystals: a new paradigm for the delivery of small molecules and bio-macromolecules
    Therapeutic deliveryFuture Science Ltd
    Jan 2018
  • A
    Anisamide-anchored lyotropic nano-liquid crystalline particles with AIE effect: a smart optical beacon for tumor imaging
    ACS applied materials interfacesAmerican Chemical Society
    Jan 2018
  • A
    Synchronized Ratiometric Codelivery of Metformin and Topotecan through Engineered Nanocarrier Facilitates In Vivo Synerg
    Advanced healthcare materials
    Jan 2018
  • C
    Multimodal lyotropic liquid crystalline nanoparticles with aggregation-induced effect for image-guided cancer chemothera
    CANCER MEDICINEWILEY
    Jan 2018
  • C
    P-gp modulatory acetyl-11-keto-β-boswellic acid based nanoemulsified carrier system for augmented oral chemotherapy of d
    Colloids and Surfaces B BiointerfacesElsevier
    Jan 2017
  • A
    Vitamin B6 tethered endosomal pH responsive lipid nanoparticles for triggered intracellular release of doxorubicin
    ACS applied materials interfacesAmerican Chemical Society
    Jan 2016
  • A
    Formulation and Evaluation of Candesartan Cilexetil Matrix Tablets
    American Journal of PharmTech Research
    Jan 2016