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Lisa Graham

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Chief Executive Officer
Seattle, Washington, United States

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Jobs verified_user 0% verified
  • Seeq Corporation
    Chief Executive Officer
    Seeq Corporation
    Nov 2021 - Current (4 years 7 months)
    Founded in 2013, Seeq is a privately held company that publishes Seeq, an application for engineers and operations analysts to rapidly find and share insights in process manufacturing data. Seeq is currently being used in the oil & gas, pharmaceutical, specialty chemical, utility, renewal energy and many other vertical industries to improve production outcomes, including yield, margins, quality, and safety. Seeq is headquartered in Seattle, Washington, with employees across the United States and sales representation in Canada, Europe, and South America.
  • Seeq Corporation
    Chief Operating Officer
    Seeq Corporation
    Oct 2020 - Dec 2021 (1 year 3 months)
    Led day-to-day execution of Seeq vision and harmony within the company.
  • Seeq Corporation
    VP, Analytics Engineering
    Seeq Corporation
    Oct 2018 - Jan 2021 (2 years 4 months)
    Led the growth and development of the analytics engineering team.
  • A
    CEO and Founder
    Alkemy Innovation Inc
    Jan 2016 - Oct 2020 (4 years 10 months)
    Alkemy Innovation Inc. is a company providing engineering services, while also partnering to develop science-based software solutions that provide specific technical guidance from key data sources. Current focus is on the pharma industry and specialty chemical industry where better, faster data access and real-time overlay of time-based variables is crucial for rapid troubleshooting and predictive model development. Alkemy Innovation Inc. also partners with companies who want to tailor their hardware and software solutions to the scientists and engineers who run the R&D, pilot, and manufacturing scale processes.
  • O
    Board of Trustees for Oregon Tech (Chair 2015-2020)
    Oregon Tech Board of Trustees
    Sep 2014 - Jun 2022 (7 years 10 months)
    Founded in Klamath Falls in 1947, the Oregon Institute of Technology is the only public 4-year institute of technology in the Pacific Northwest. Oregon Tech provides degree programs in engineering and health technologies, management, communication and applied sciences.
  • PARADIGMisr
    Chief Scientist
    PARADIGMisr
    Aug 2014 - Nov 2015 (1 year 4 months)
  • PARADIGMisr
    Chief Scientist
    PARADIGMisr
    Aug 2014 - Nov 2015 (1 year 4 months)
  • B
    Senior Vice President
    Bend Research
    Feb 2012 - Mar 2014 (2 years 2 months)
    Developed growth of biotherapeutics and new technology areas for the company
  • B
    Vice President and COO
    Bend Research
    Jan 2009 - Feb 2012 (3 years 2 months)
    Managed key operational aspects of the company.
  • B
    Vice President, Engineering
    Bend Research
    Jan 2008 - Dec 2009 (2 years)
  • B
    Senior Research Chemical Engineer
    Bend Research
    Jan 2002 - Dec 2008 (7 years)
  • Dow
    Senior Chemical Engineer
    Dow
    Sep 1999 - Jan 2002 (2 years 5 months)
Education verified_user 0% verified
  • Oregon State University
    Ph.D., Chemical Engineering, Chemical Engineering
    Oregon State University
    Jan 1996 - Dec 1999 (4 years)
    Chemical Engineering
  • Oregon State University
    Bachelor of Science - BS, Chemical Engineering, Chemical Engineering
    Oregon State University
    Oregon State is a leading research university located in one of the safest, smartest, greenest small cities in the nation. Situated 90 miles south of Portland, and an hour from the Cascades or the Pacific Coast, Corvallis is the perfect home base for exploring Oregon's natural wonders.
Projects (professional or personal) verified_user 0% verified
  • M
    Mentor - Creative Destruction Lab (CDL) - Foster School of Business, University of Washington, WA.
    Sep 2023
    Creative Destruction Lab (CDL) is a nonprofit organization that delivers an objectives-based program for massively scalable, seed-stage, science- and technology-based companies. Its nine-month program allows founders to learn from experienced entrepreneurs, increasing their likelihood of success. CDL-Seattle pairs participating founders with accomplished entrepreneurs and engineers who have decades of experience in manufacturing and want to help the next generation succeed. CDL mentors include accomplished entrepreneurs, experienced operators, and active angel and venture investors. Mentors meet ventures every eight weeks at each site to help founders set objectives over the program’s nine-month duration. https://foster.uw.edu/centers/creat
  • C
    Chair of the 2023 ISPE Annual Meeting
    Dec 2022 - Nov 2023 (1 year)
    The 2023 ISPE Annual Meeting & Expo will usher in a revitalized focus on excellence, modernization, and harmonization in pharmaceutical science and manufacturing across the globe, offering pharma professionals the opportunity to engage in industry-critical conversations. A comprehensive education program provides attendees with technical sessions on the latest developments in supply chain, operations, facilities, equipment, information systems, product development, production systems, quality systems, regulatory guidance and cutting-edge industry innovations. This signature event draws pharmaceutical and biopharmaceutical professionals at all levels of the industry from emerging leaders to the most senior executives in drug manufacturing, s
  • E
    Education Chair on the ISPE Annual Meeting Committee
    Dec 2021 - Nov 2022 (1 year)
    https://ispe.org/pharmaceutical-engineering/ispeak/digital-transformation-control-prediction-and-optimization
  • C
    Commercializing Continuous Processing (CCP) Panel Session Leader (2021)
    Jan 2021 - Feb 2021 (2 months)
    From Implementation to Digitalization: Reaping Commercial Continuous Processing Benefits to Ensure Manufacturing Capacity, Accelerate Speed-to-Market & Optimize Flexible cGMP Manufacturing. The 5th Commercializing Continuous Processing in Pharma 2021 will reunite the growing CCP community to discuss how to accelerate adoption of continuous processing in a GMP environment.
  • E
    Education Co-Chair on the 2021 ISPE Annual Meeting Program Committee
    Dec 2020 - Nov 2021 (1 year)
    The 2021 ISPE Annual Meeting & Expo will usher in a revitalized focus on excellence, modernization, and harmonization in pharmaceutical science and manufacturing across the globe, offering pharma professionals the opportunity to engage in industry-critical conversations. A comprehensive education program provides attendees with technical sessions on the latest developments in supply chain, operations, facilities, equipment, information systems, product development, production systems, quality systems, regulatory guidance and cutting-edge industry innovations. This signature event draws pharmaceutical and biopharmaceutical professionals at all levels of the industry from emerging leaders to the most senior executives in drug manufacturing, s
  • E
    Education Co-Chair on the 2020 ISPE Annual Meeting Program Committee
    Dec 2019 - Nov 2020 (1 year)
    This signature event draws pharmaceutical and biopharmaceutical professionals at all levels of the industry from young professionals to the most senior executives in drug manufacturing, supply chain, devices and equipment and services, and global regulatory agencies. The conference offers a large exhibition hall offering the latest technologies and services for the pharmaceutical industry.
  • C
    Commercializing Continuous Processing (CCP) Panel Session Leader (2019-2020)
    Jan 2019 - Jan 2020 (1 year 1 month)
    Coming to the 4th Annual CCP Summit, we will continue to explore scientific and technology advancements that can help eliminate bottlenecks, and more importantly, will address the quality, upfront investment and business rationale behind the ‘switch’. Bringing together small molecules and biologics experts under one roof for knowledge and experience exchange. Returning to Boston for the 4th time on Jan 28 – 30, 2020
  • C
    Commercializing Continuous Processing (CCP) Panel Session Leader (2018-2019)
    Jan 2018 - Jan 2019 (1 year 1 month)
    Tailoring your Technology and Business Strategy for Success," 3rd Annual Commercializing Continuous Processing in Pharma (CCP) Conference, Boston, MA, January 30, 2019
  • W
    Webinar: Real-Time Process Control for Healthy, High-Purity Water Systems
    Jan 2018 - Mar 2018 (3 months)
  • I
    ISPE Track Director for the Process Development and Manufacturing (PDM) Track (2018-2019) (Co-Director 2017-2018)
    Nov 2017 - Nov 2019 (2 years 1 month)
    The 2019 ISPE Annual Meeting & Expo will focus on modernization, globalization, and transformation in pharmaceutical science and manufacturing across the globe, offering pharma professionals the opportunity to engage in industry-critical conversations. This signature event draws pharmaceutical and biopharmaceutical professionals at all levels of the industry from young professionals to the most senior executives in drug manufacturing, supply chain, devices equipment and services, and global regulatory agencies. ISPE Process Development and Manufacturing Track Blog: PHARMACEUTICAL ENGINEERING ISPEAK AGILE LAB TO LAUNCH, CONTINUOUS MANUFACTURING, & NOVEL THERAPIES: THE FUTURE OF PHARMA PROCESS DEVELOPMENT & MANUFACTURING iSpeak Blog 27 Augus
  • I
    ISPE Track Co-Director for the Process Development and Manufacturing (PDM) Track (2017-2018)
    Nov 2017 - Nov 2018 (1 year 1 month)
    Over 2,400 attendees from 31 countries gathered in Philadelphia for the 2018 ISPE Annual Meeting & Expo. The opening plenary on Sunday, 4 November provided a strong kickoff to the four-day conference, whose theme of “Vision to Reality” focused on the promise of new developments that ISPE members are helping the pharmaceutical industry tackle.
  • W
    Webinar: Ensuring a Healthy Water System 24 x 7
    Aug 2017 - Nov 2017 (4 months)
    This webinar will discuss the process and benefits of implementing online water bioburden analyzers (OWBAs) on pharmaceutical grade water loops to provide a real-time view of the water system health. Until recently, real-time bioburden measurement was unavailable and users needed to rely on retrospective information. We will review a case study that illustrates how to leverage this new missing “puzzle piece” of data from Azbil BioVigilant’s IMD-W™ OWBA system and, in concert with data from other sensors on a water loop that monitor items like total organic carbon, process flowrates, system pressures, sanitization, and valve operation, gain a more meaningful view. This case study will show how to distill this data to effectively drive deci
  • C
    Commercializing Continuous Processing (CCP) Panel Session Leader (2017-2018)
    Jan 2017 - Jan 2018 (1 year 1 month)
    "Establishing a Winning Case for Investment," 2nd Annual Commercializing Continuous Processing in Pharma (CCP) Conference, Boston, MA, January 30-February 1, 2018.
  • N
    Nationally-Focused STEM Ecosystems Initative
    Nov 2015 - Feb 2016 (4 months)
    On behalf of Oregon (and the Governor's STEM Investment Council), I had the chance to participate in this kick off meeting. There were 27 STEM Learning Ecosystems gathered in Washington, D.C. and they represented the inaugural group selected by the STEM Funders Network for support as part of a larger commitment that will grow to support 100 ecosystems in its first three years. These groups are forming a diverse set of communities from across the country by creating engaging, real-world STEM learning experiences. Each of the 27 networks should be receiving hands-on technical assistance individualized to the needs of each community from the STEM Funders Network. "The President has called for all of us to think of creative and effective ways o
  • O
    Oregon Tech Board of Trustees - Board Chair
    Sep 2014 - Jun 2022 (7 years 10 months)
    Founded in Klamath Falls in 1947, the Oregon Institute of Technology is the only public 4-year institute of technology in the Pacific Northwest. Oregon Tech provides degree programs in engineering and health technologies, management, communication, and applied sciences. While official terms start immediately, the Trustees will assume governance of Oregon Tech on July 1, 2015 from the State Board of Higher Education, whose structure sunsets on June 30, 2015. Elected Board Chair January 21, 2015.
  • O
    Oregon State Board of Higher Education
    Jun 2014 - Jun 2015 (1 year 1 month)
    The Oregon State Board of Higher Education Board serves the state of Oregon in terms of budget evaluations and institutional decisions for the major and regional Oregon universities. In its final term of service (through June 2015), the Board will continue to assist with the transition toward individual governing boards. The Board is composed of a number of members, including public members appointed by the Governor and confirmed by the Oregon State Senate.
  • B
    Biomanufacturing Summit
    Jan 2014 - Dec 2014 (1 year)
    January 30th – January 31st, 2014 Bend Research Highlights Biotherapeutics Capabilities at the Biomanufacturing Summit in San Diego, CA. Bend Research Inc., a leading independent scientific development and manufacturing company, will participate in several events in 2014 focused on achieving value and advancing health through innovations in biotherapeutics. I'll be presenting “Leveraging coupled bioreactor analytics, automated sampling and applied mathematics to improve cell culture and bioreactor operations” at 11:45am PST on Friday, January 31st. If you’re attending the summit, please stop by or visit us at our booth #35.
  • 1
    18th Annual Drug Delivery Partnerships Conference
    Jan 2014 - Feb 2014 (2 months)
    January 27th – January 29th, 2014 Bend Research Highlights Biotherapeutics Capabilities at the 18th Annual Drug Delivery Partnerships Conference in Boca Raton, FL. Bend Research Inc., a leading independent scientific development and manufacturing company, will participate in several events in 2014 focused on achieving value and advancing health through innovations in biotherapeutics. I'll present “Advance Your Compound Using Science and Engineering Excellence” at 4:30pm EST on Tuesday, January 28th. If you’re attending the conference, please stop by.
  • B
    Bend Research Presents Advanced Bioprocessing Technologies at Upcoming Industry Meetings and Webinar
    Aug 2013 - Dec 2013 (5 months)
    Bend Research Inc.announced its participation in presentations at upcoming industry gatherings that will focus on its newly developed full-spectrum Process Analytical Technology (PAT) solutions for improved bioreactor operations. “ At Bend Research we are delivering innovative and transformative technologies for achieving target product quality through science and engineering,” said Dr. Lisa Graham, senior vice president of Bend Research. Bend Research scientists will discuss their PAT solutions for improved bioreactors at a series of upcoming international meetings in Aug and Sept, including a technical webinar on Sept 26th:
  • C
    Cell Line Development and Engineering
    May 2013 - Dec 2013 (8 months)
    Bend Research Highlights Biotherapeutics Capabilities at IBC's 9th Annual Cell Line Development and Engineering Conference Bend Research Inc., a leading independent scientific development and manufacturing company, announced it will participate in several May events focused on achieving value and advancing health through innovations in biotherapeutics. I'll be chairing the session titled, “Developing Cell Lines for Biosimilars” and will present a talk titled, “Data Integration Methodology that Leverages Coupled Bioreactor Analytics, Automated Sampling, and Applied Mathematics to Redefine Bioreactor Operation: Case Study Example Illustrating Impact on Cell Culture Productivity,”
Awards verified_user 0% verified
  • P
    Influential Women in Manufacturing (IWIM) Honoree (2019)
    Putman Media
    May 2019
    Influential Women in Manufacturing (IWIM) is a recognition program honoring women who are effecting change in the manufacturing and industrial production space. Founded by three editors from Putman Media, Erin Hallstrom, Alexis Gajewski, and Christine LaFave Grace, IWIM celebrates the wide-ranging, needle-moving accomplishments of women in industry and looks to spark conversations about best practices for building the workforce that will continue to drive the manufacturing industry forward. https://www.influentialwomeninmanufacturing.com/iwim-honorees-announcement-2019/?utm_content=92705234&utm_medium=social&utm_source=linkedin&hss_channel=lcp-3126445 (https://www.influentialwomeninmanufacturing.com/about/)
  • O
    Oregon State University Academy of Distinguished Engineers (2016)
    Oregon State University College of Engineering
    Mar 2016
    "In 1998, the College introduced the annual Oregon Stater awards to honor outstanding alumni and friends for their contributions to the engineering profession and to Oregon State University. There are three award categories determined by length of career and accomplishments: Membership in the OSU Academy of Distinguished Engineers is awarded to mid-career Oregon Staters who have sustained distinguished contributions to the profession, field, OSU, or society at large. They have at least twenty years of experience beyond the BS and are still practicing their profession." http://engineering.oregonstate.edu/lisa-graham-2016-academy-distinguished-engineers
  • Oregon State University
    Oregon State University Council of Early Career Engineers (2010)
    Oregon State University
    Feb 2010
    The OSU Council of Outstanding Early Career Engineers is reserved for Oregon Staters who have distinguished themselves through professional practice and/or service to OSU, the profession, or society at large. These individuals have made early career contributions that identify them as future leaders in their profession or field. They have less than 20 years of professional experience beyond receipt of their bachelor’s degree. Dr. Lisa J. Graham earned a BS in Chemical Engineering from Oregon State University in 1995 and in 1999 completed her PhD. Dr. Graham joined Union Carbide, a Subsidiary of the Dow Chemical Company as Senior Engineer in a supervisory role. Lisa received recognition awards for technical achievement and leadership from Un
Publications verified_user 0% verified
  • I
    Digital Transformation: Control, Prediction, and Optimization
    International Society of Professional Engineers ISPE Annual Meeting Blog
    Jan 2022
  • S
    Leadership in the digital era: A Q&A with new Seeq CEO Dr. Lisa J. Graham
    Smart Industry
    Jan 2022
  • A
    Getting the Most Out of Digital Transformation
    Automationcom
    Jan 2021
  • O
    Harnessing Machine Learning
    Oilfield Technology
    Jan 2020
  • P
    The Evolution of Analytics: How advanced analytics is being used to drive desired business outcomes in pharma”
    Pharma Manufacturing
    Jan 2020
  • P
    Advanced Analytics Delivers Continuous Manufacturing Innovation
    PharmTech
    Jan 2020
  • i
    Supporting Pharma Innovation Through Analytics
    iSpeak Blog
    Jan 2020
  • i
    Agile Lab to Launch, Continuous Manufacturing, & Novel Therapies: The Future of Pharma Process Development & Manufacturi
    iSpeak Blog
    Aug 2019
    The needs of patients provide the impetus to challenge the notion of “this is the way we’ve always done it”. Many of our colleagues are taking on the challenge of rethinking the old ways. They are collaborating with each other and the regulatory agencies to take effective steps to remain at the forefront of regulatory science and innovation. Why? In order to ensure the continued delivery of effective medicines.... More at the link provided...
  • INTECH Process Automation
    Empowering an Effective PAT Methodology: Operationalizing advanced analytics for data-driven decision making
    INTECH Process Automation
    Jan 2019
  • P
    Data Analytics Moves Beyond Dilbert: Why pharma manufacturers shouldn’t get stuck in a comic
    Pharma Manufacturing
    Jan 2019
  • P
    The Human-Machine Matchup
    Pharma Manufacturing
    Jan 2019
  • B
    Of Microbrews and Medicines: Understanding Their Similarities and Differences in Bioprocessing Can Help Improve Yields a
    Bioprocess International
    Jan 2018
  • P
    Dealing with Disparate Data: Choosing advanced solutions rather than manual data analysis helps improve quality insights
    Pharmaceutical Manufacturing
    Jan 2018
  • P
    Implementing a Culture-Driven Data Analytics Approach to Support Tech Transfer and Product Launch
    Pharmaceutical Processing
    Nov 2017
    The right data analytics solution is not a collection of individual applications reserved for just a few ‘expert’ individuals within a company. Data analytics is essential to survival in today’s high-speed and competitive R&D and manufacturing world. Effectively managing manufacturing process data, along with the full portfolio of data collected during the pilot to commercial transition, and post-launch, is critical for launching a successful and profitable product. A facile data analytics solution can support the required prevention, detection and response, risk reduction and regulatory stewardship workflows to support product evolution. This requires effective connectivity to the supporting data sets, necessary when performing tech transf
  • P
    Creating Value from Data Assets
    Pharmaceutical Manufacturing
    Sep 2017
    Designing the optimal data asset management and analytics approach for your organization is key for improving operations, compliance and safety
  • B
    Deriving Insight at the Speed of Thought: Advancing Medicine Production Through an Effective Data Analytics Methodology
    BioProcess Journal
    May 2017
    In a world already awash with technology, life sciences companies are racing to add more automation and data sources, while ironically often spending less time focused on process improvements. In some cases, these two opposing actions can still produce positive results by: (a) reducing manual labor to minimize data translation errors; (b) adding sensors to gather a new kind of data about a protein or a process; or (c) implementing high-throughput techniques for biopharmaceutical development. But what about those situations where collecting new data is not so positive? Does it really make sense to run experiments without the full benefits of accessing accumulated data or gathering new data? Or to proceed without the insights gained from a co
  • B
    Leveraging Data Analytics Innovations to Improve Process Outcomes
    BioPharm International
    Nov 2016
    "New data analytics tools help solve complex problems in a biotherapeutic development process." Scientists and engineers working with R&D, pilot-, and production-scale processes in the life-sciences industries need new ways to harness the potential of the data they gather to drive innovation. Crucial elements include: - Understanding the process - Identifying the appropriate process sensors and technology to acquire and store data - Connecting disparate data sources - Implementing data analytics and visualization applications to analyze and make changes for improving the quality and quantity of medicines produced.
  • B
    A novel approach for using dielectric spectroscopy to predict viable cell volume (VCV) in early process development
    Biotechnology Progress
    Jan 2014
    Online monitoring of viable cell volume (VCV) is essential to the development, monitoring, and control of bioprocesses. The commercial availability of steam-sterilizable dielectric-spectroscopy probes has enabled successful adoption of this technology as a key noninvasive method to measure VCV for cell-culture processes. Technological challenges still exist, however. For some cell lines, the technique's accuracy in predicting the VCV from probe-permittivity measurements declines as the viability of the cell culture decreases. To investigate the cause of this decrease in accuracy, divergences in predicted vs. actual VCV measurements were directly related to the shape of dielectric frequency scans collected during a cell culture. The changes
  • I
    Drawdown of floating solids in stirred tanks: Scale-up study using CFD modeling
    International Journal of Pharmaceutics
    Jan 2011
    This work shows development of a scale up correlation using computational fluid dynamic (CFD) simulations for floating solids drawdown operation in stirred tanks. Discrete phase modeling (DPM) simulations were used in conjunction with the lab scale experimental measurements to develop a semi-empirical correlation for the prediction of rate of drawdown of floating solid particles. The rate was correlated to average liquid velocity at the free liquid surface. Since, this correlation is based on a fundamental hydrodynamic parameter, velocity, rather than an operating parameters such as the impeller speed, it can be used for a variety of impeller types and tank geometries. The correlation was developed based on the data obtained from the 2 L ta
  • C
    Pharmaceutical process/equipment design methodology case study: Cyclone design to optimize spray-dried-particle collecti
    Computers Chemical EngineeringElsevier
    Apr 2010
    This paper describes a case study using a cyclone-design methodology to increase cyclone collection efficiency for spray-dried dispersions (SDDs) for pharmaceutical applications. The six-step methodology combines the use of classical cyclone design (CCD) correlations and computational fluid dynamics (CFD) modeling techniques. By combining these techniques, the methodology avoids the limitations inherent with the use of either technique alone and represents an improved alternative to conventional trial-and-error methods. Specifically, the methodology increases the efficiency of the design process by reducing (1) computational time; (2) experimental time (i.e., the need for numerous development runs); and (3) the use of costly active pharmace
  • J
    A Model-Based Methodology for Spray-Drying Process Development
    J Pharm Innov
    Jul 2009
    Solid amorphous dispersions are frequently used to improve the solubility and, thus, the bioavailability of poorly soluble active pharmaceutical ingredients (APIs). Spray-drying, a well-characterized pharmaceutical unit operation, is ideally suited to producing solid amorphous dispersions due to its rapid drying kinetics. This paper describes a novel flowchart methodology based on funda- mental engineering models and state-of-the-art process characterization techniques that ensure that spray-drying process development and scale-up are efficient and require minimal time and API. This methodology offers substan- tive advantages over traditional process-development methods, which are often empirical and require large quantities of API and long
  • A
    Predicting Liquid Atomization: Simulation can be used as a predictive spray characterization tool.
    ANSYS Advantage
    Jan 2007
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