A
Alessandra DiMauro
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Missouri, United States
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Résumé
Jobs
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Doctoral ResearcherWashington University in St. LouisSep 2020 - Current (6 years 2 months)Evaluated the role of receptor tyrosine kinase DDR2 in endothelial cells, identifying its contribution to tumor angiogenesis and metastatic progression in breast cancer under the guidance of Dr. Gregory Longmore, MD. Developed and optimized 5+ robust and reproducible assays enabling preclinical evaluation of target receptor as a pro-angiogenic target and supporting target validation decisions. Generated and characterized 4+ stable cell lines from primary murine tumors. Analyzed and interpreted complex datasets to inform experimental strategy and next-step decision making. Communicated findings through written reports, internal presentations, and external scientific meetings. Mentored junior researchers, contributing to overall lab productiv- MCreative Engagement InternMerck & Co.Apr 2020 - Aug 2020 (5 months)Collaborated with the Imagine@Merck team to improve scientific data presentation and narrative clarity. Applied structured storytelling frameworks across various research departments to translate complex technical data to varying audiences.
- Drug Concept Discovery InternBoehringer IngelheimApr 2019 - Aug 2019 (5 months)Supported early-stage drug discovery efforts within the Immunology and Respiratory Disease department by screening antibodies for their ability to inhibit potential therapeutic targets. Contributed to target assessment and assay workflows within a large-pharma discovery environment.
- Undergraduate Student ResearcherUniversity of RochesterAug 2017 - May 2020 (2 years 10 months)Conducted mechanistic studies on hormone-driven tumor growth, identifying dopamine receptor-mediated signaling pathways regulating leiomyoma proliferation under the guidance of Dr. Stephen Hammes, MD PhD. Supported molecular and cellular experiments, culminating in an honors thesis in research as well as a first author publication in a peer reviewed journal.
Education
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- Doctor of PhilosophyWashington University in St. LouisSep 2020 - May 2026 (5 years 9 months)Cancer Biology
- Bachelor of ScienceUniversity of RochesterAug 2016 - May 2020 (3 years 10 months)Cell and Developmental Biology
- Bachelor of ArtUniversity of RochesterAug 2016 - May 2020 (3 years 10 months)British and American Literature
Awards
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- Whipple Science and Research ScholarshipUniversity of RochesterAug 2016 - May 2020 (3 years 10 months)Merit based scholarship awarded to undergraduate students to supports students pursuing research in biomedical or science-related fields, honoring the legacy of the first dean of the School of Medicine and Dentistry, George Whipple.
- James E Casey ScholarshipUnited Parcel ServiceAug 2016 - May 2020 (3 years 10 months)The James E. Casey Scholarship program, established in 1963, provides college merit-based financial support to children of UPS employees, often in partnership with the National Merit Scholarship Corporation (NMSC).
Publications
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- DDDR2 plays a cell-intrinsic role in breast tumor angiogenesis and metastasis. Under Review.Jan 2026 - Current (10 months)
- EEx-vivo Microfluidic Model identifies a Role for Shear Stress During Ovarian Tumor Cell Attachment to Peritoneal MesotheDec 2025
- WDDR2 confers ferroptosis resistance to cancer-associated fibroblasts and attenuates PARPi sensitivity of ovarian tumor cWashington UniversitySep 2025
- CCadherin-1-mediated communication at the leader-follower boundary controls mouse breast tumor organoid collective migratJan 2025
- PProlactin is Expressed in Uterine Leiomyomas and Promotes Signaling and Fibrosis in Myometrial Cells.Jan 2022
- BBilateral Pheochromocytomas in a Patient with Y175C Von Hippel-Lindau Mutation.Jan 2018