Tobias Ralph Shipley
About
Detail
Medical Biology Graduate | Quality Assurance Specialist | Quality Systems Management at Lonza
Visp, Valais, Switzerland
Contact Tobias regarding:
work
Full-time jobs
Résumé
Jobs
verified_user
0% verified
QA SpecialistLonzaSep 2025 - Current (1 year 2 months)Quality Systems Management QA Specialist- Junior QA Specialist - Global External QualityRocheFeb 2024 - Feb 2025 (1 year 1 month)- IMP Quality Operations – Assigned to the IMP Quality team, overseeing quality operations in the production, packaging, and distribution of IMPs for use in clinical trials. - Complaint investigations – Managed 30+ cases of defective medical devices (syringes, autoinjectors, vials), liaising with CMOs Novartis and Vetter Pharma. - Vendor-initiated change management – Conducted 50+ vendor change impact assessments for the Basel Biologics Drug Substance Production Unit using Veeva QMS and SAP. - Change control owner – Supported internal audits, implemented CAPAs and managed batch records from decommissioned CDMOs to ensure regulatory compliance and data integrity. - End-to-end management of GMP documentation – Spearheaded the full lifecycle m
- Research Assistant; WHO Collaborating Centre for Immunology Research and TrainingWorld Health OrganizationJun 2022 - Feb 2023 (9 months)- Led a research project on parasite drug resistance, designing and conducting 40+ experiments using analytical methodologies (Flow cytometry, RNA-seq, Western blot, and ELISA) and in vivo experimentation. - Discovered and validated three novel proteins contributing to resistance and presented findings to 200+ researchers at an annual immunology conference. Publication: Díaz-Varela, M. et al. (2024). “The different impact of drug-resistant leishmania on the transcription programs activated in neutrophils”. iScience. Show less
- Research Assistant; University Centre of Legal MedicineUniversity of lausanneOct 2021 - Dec 2021 (3 months)- Collaborated with Institute of Legal Medicine members in Lausanne and Geneva to optimised an in vitro activity-based protein methodology for profiling serine hydrolases in human blood samples for diagnostic applications. Publication: Maret, E. et al. (2024). “Activity-based proteome profiling of serum serine hydrolases: Application in paediatric abusive head trauma”. Proteomic Clinical Applications.
- Internship in Compliance & QualificationMerck GroupSep 2020- Qualified GxP suppliers using SQQs and inspected biopharmaceutical production equipment to ensure GMP compliance.
- Internship in Computational BiologySIB Swiss Institute of BioinformaticsJul 2020 - Aug 2020 (2 months)- Contributed to the multinational BEAt-DKD project (31 academic and private partners) with colleagues from Lund University, Sweden, and the University of Bristol, UK - Used UniProt and Cytoscape bioinformatic software to visualise gene expression networks in diabetic kidney disease and identify 10+ potential biomarkers with therapeutic potential.
- Sales And Marketing AssociateEdmistonJun 2019- Supported sales and marketing at ECYP open day; showcasing products, engaging clients, and facilitating four charter contracts by connecting clients with brokers through networking. - Conducted market research to expand the charter fleet for new client segments.
- Healthcare AssistantEMS Château des NovallesAug 2017- Assisted care home staff with tasks such as personal hygiene care for the residents, meal preparation, interactive activities, and wheelchair service
- Medical StudentAl Zahra Pvt. Hospital DubaiMay 2016 - Feb 2017 (10 months)- Shadowed orthopaedic surgeon Dr Deepak Bhatia during patient consultations, clinical procedures and observed multiple surgical operations. - Interacted with sales representatives showcasing a novel biodegradable filament suture.
Education
verified_user
0% verified
- University of Lausanne - UNIL — Master of Science - MSc, Medical Biology, 5.5/6University of Lausanne - UNILJan 2021 - Dec 2023 (3 years)Master's degree in Medical Biology with a specialisation in Immunology and Cancer. Master Thesis: "The impact of Leishmania (Viannia) panamensis drug resistance on neutrophil function and pathogenicity of leishmaniasis." Leishmaniasis is a neglected tropical disease caused by Leishmania parasites, presenting a global public health concern with increasing drug resistance to first-line treatments such as meglumine antimoniate (MA). Although the role of neutrophils in Leishmania drug resistance remains unclear, recent studies suggest that the MA susceptibility phenotype of Leishmania parasites affects the production of specific neutrophil drug resistance mediators. Our research indicates that the interaction between MA-resistant and MA-suscept
- University of Nottingham — Bachelors of Science - BSc Biochemistry and Molecular Medicine, First Class with HonoursUniversity of NottinghamJan 2018 - Dec 2021 (4 years)Bachelor Thesis: "A review of SARS-CoV-2 B.1.1.7, B.1.351 and P.1 variants and their interactions with ACE2 and neutralising antibodies." The novel SARS-CoV-2 virus emerged in Wuhan, China, and has spread globally, giving rise to concerning variants like the UK (B.1.1.7), South African (B.1.351), and Brazilian (P.1). These variants have mutations in the spike protein receptor binding domain (RBD), leading to more robust binding to human ACE2 receptors and potential immune evasion. Among them, the B.1.351 variant is particularly worrisome due to a combination of mutations that enhance receptor binding and immune resistance. Show less
- Haut-Lac International Bilingual School — IB Diploma, HIGH SCHOOL/SECONDARY DIPLOMAS AND CERTIFICATES, 35 pointsHaut-Lac International Bilingual SchoolJan 2016 - Dec 2018 (3 years)IB Subject and Grade: Biology - 6 Geography- 6 French- 6 Maths- 5 English- 5 Chemistry- 4 Bonus Points- 3/3 Final IB Grade: 35 points