William Trump

William Trump

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Co-Founder, Head of Product
San Francisco, California, United States

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Jobs verified_user 0% verified
  • Cornucopia Biosciences
    Co-Founder, Head of Product
    Cornucopia Biosciences
    Jan 2026 - Current (10 months)
  • Spring Science
    Sr. Director and Head of Laboratory Operations
    Spring Science
    May 2023 - Jan 2025 (1 year 9 months)
    Running a high throughput screening lab that uses laboratory automation and artificial intelligence to drive new insights to drug development.
  • Spring discovery
    Lead Process Engineer
    Spring discovery
    Jan 2020 - Jun 2023 (3 years 6 months)
  • Myriad Genetics
    Process Engineering Manager
    Myriad Genetics
    Jul 2019 - Jan 2020 (7 months)
  • Myriad Genetics
    Staff Process Development Engineer
    Myriad Genetics
    Jul 2018 - Jul 2019 (1 year 1 month)
    Sr. Engineer responsible for applications development on our state-of-the-art fully automated robotics workcell. Worked primarily with Tecan and Agilent systems with an emphasis on next-generation sequencing sample preparation workflows.
  • V
    Principal
    Van Trump Consulting
    Jun 2018 - Current (8 years 5 months)
    Providing consulting services in the biotech industry for Laboratory Automation, Operations, Data Managment and Operational Analytics.
  • E
    Director Of Process Engineering
    EpiBiome
    Mar 2017 - Jun 2018 (1 year 4 months)
    Building automated laboratory solutions to accelerate the discovery and development of bacteriophage therapeutics.
  • Illumina
    Sr. Manager, Engineering
    Illumina
    May 2016 - Mar 2017 (11 months)
    Leader of the Process Development Engineering Team within the Reproductive and Genetic Health Business Unit for non-invasive prenatal screening. Responsible for development, sustainment and product support for all laboratory hardware and process/automation software.
  • Illumina
    Engineering Manager
    Illumina
    May 2015 - May 2016 (1 year 1 month)
    Primary Role:
    - Led automation development for assay projects
    - Conducted systems integration programming for interfaces between robotic systems and centralized control software.

    Secondary Role:
    - Led the equipment support team within our bay area clinical operations group. This team oversees, maintains, and repairs a fleet of liquid handling robots and NGS Sequencing Platforms.
  • Illumina
    Sr. Engineer - Process Development
    Illumina
    Jun 2014 - May 2015 (1 year)
    Primary Role:
    - Develop automated laboratory workflows for NGS diagnostic tests
    - Program Liquid Handling robotics platforms
    - Primary liaison between the laboratory process development team and our assay bioinformatics team.

    Secondary Roles:
    - Provide technical and operations support for our CLIA certified NIPT testing lab
    - Manage the Equipment Engineering team for our Redwood City site.
  • Illumina
    Business Systems Analyst
    Illumina
    Dec 2011 - Jan 2013 (1 year 2 months)
    Primary role:
    - Provide data analysis and statistical validation support for the production of gene sequencing platforms.
    - Provide data managment support, scripting, data mining, and automation.
    - Managed production databases (Sharepoint, DevTrack)

    Secondary roles:
    - Led initiatives for process improvment utilizing DMAIC, 8D, and Lean approaches.
    - Provided platform engineering support using a wide range of computational and analytical tools.

    Awards:
    - 2012 Q3 Values award winner
  • Intel
    Research Engineer
    Intel
    Apr 2011 - Dec 2011 (9 months)
    Device characterization on electrochemical biosensors.

    Integrated Biosystems Lab, Biomeasurements
  • Saint Marys College of California
    Lecturer
    Saint Marys College of California
    Feb 2011 - May 2011 (4 months)
    Part-time instructor of Human Physiology Laboratory
  • UC Irvine
    Research Assistant
    UC Irvine
    Sep 2005 - Mar 2011 (5 years 7 months)
    Investigated the biomechanics and sensory physiology of fluid flow sensing by the lateral line organ in fish.
    Responsibilities included:
    - Mathematical Modeling of microfluidics and fluid-structure interactions (FSI)
    - Pioneering novel approaches in optical microscopy
    - Generation of MATLAB programs to facilitate equipment interfacing and allow the generation of large datasets by lab technicians.
    - Fluorescence microscopy using whole mount in situ functional labels
    - Prototyping of mechanical and electrical equipment including: headstage amplifiers, microscope flow chambers, large scale flow chambers
    - Primary manager of lab animal colonies

    Grants/Awards:
    -
  • University of California Irvine
    Teaching Assistant/Associate
    University of California Irvine
    Sep 2005 - Sep 2010 (5 years 1 month)
    - Managed the instruction of an upper division Physiology Laboratory

    - Assisted in the instruction of 11 courses including Mechanical Physiology, Intro to Laboratory and Science Writing, Exercise Physiology, Philosophy of Biology, among others

    - Awarded the 2010 Edward Steinhaus Teaching Award in Ecology and Evolutionary Biology
  • Union Pacific Railroad
    Engineering Intern
    Union Pacific Railroad
    Jun 2005 - Aug 2005 (3 months)
    - Summer internship in the Construction Engineering division
    - Assisted with the oversight and management of a large rail-to-truck intermodal complex
    - Observed progress and verified compliance to company specifications
  • UNIVERSITY OF CALIFORNIA BERKELEY
    CalSO Counselor
    UNIVERSITY OF CALIFORNIA BERKELEY
    Jun 2004 - Aug 2004 (3 months)
Education verified_user 0% verified
  • UC Irvine
    Ph.D, Biological Sciences (Sensory Biomechanics)
    UC Irvine
    Jan 2005 - Dec 2011 (7 years)
    Additional coursework: - Medical Physiology: UC Irvine School of Medicine - Neural Systems and Behavior: MBL (Woods Hole) - Functional Morphology of Fish: Friday Harbor (U Wash)
  • UNIVERSITY OF CALIFORNIA BERKELEY
    BS, Bioengineering (Biomechanics)
    UNIVERSITY OF CALIFORNIA BERKELEY
    Jan 2001 - Dec 2005 (5 years)
Publications verified_user 0% verified
  • N
    Morphological map of under- and overexpression of genes in human cells
    Nature Methods
    Jun 2025
    Cell Painting images offer valuable insights into a cell’s state and enable many biological applications, but publicly available arrayed datasets only include hundreds of genes perturbed. The JUMP Cell Painting Consortium perturbed roughly 75% of the protein-coding genome in human U-2 OS cells, generating a rich resource of single-cell images and extracted features. These profiles capture the phenotypic impacts of perturbing 15,243 human genes, including overexpressing 12,609 genes (using open reading frames) and knocking out 7,975 genes (using CRISPR–Cas9). Here we mitigated technical artifacts by rigorously evaluating data processing options and validated the dataset’s robustness and biological relevance. Analysis of phenotypic profiles r
  • i
    A combined AI and cell biology approach surfaces targets and mechanistically distinct Inflammasome inhibitors
    iScience
    Dec 2024
    Inflammasomes are protein complexes that mediate innate immune responses whose dysregulation has been linked to a spectrum of acute and chronic human conditions, which dictates therapeutic development that is aligned with disease variability. We designed a scalable, physiologic high-content imaging assay in human PBMCs that we analyzed using a combination of machine-learning and cell biology methods. This resulted in a set of biologically interpretable readouts that can resolve a spectrum of cellular states associated with inflammasome activation and inhibition. These methods were applied to a phenotypic screen that surfaced mechanistically distinct inflammasome inhibitors from an annotated 12,000 compound library. A set of over 100 inhibit
  • b
    A multi-phenotype system to discover therapies for age-related dysregulation of the immune response to viral infections
    bioRxiv
    Jul 2020
    Age-related immune dysregulation contributes to increased susceptibility to infection and disease in older adults. We combined high-throughput laboratory automation with machine learning to build a multi-phenotype aging profile that models the dysfunctional immune response to viral infection in older adults. From a single well, our multi-phenotype aging profile can capture changes in cell composition, physical cell-to-cell interaction, organelle structure, cytokines, and other hidden complexities contributing to age-related dysfunction. This system allows for rapid identification of new potential compounds to rejuvenate older adults’ immune response. We used our technology to screen thousands of compounds for their ability to make old immun
  • I
    The Lateral Line System is Not Necessary for Rheotaxis in the Mexican Blind Cavefish (Astyanax fasciatus)
    Integrative and Comparative Biology
    Jul 2013
    Fish resist being swept downstream by swimming against a current. Mexican blind cavefish (Astyanax fasciatus) exhibit this innate behavior, rheotaxis, without the aid of vision, but it has been debated whether this ability requires sensing flow with the lateral line system. We tested the role of the lateral line by comparing swimming in a flow chamber in a group of cavefish with a compromised lateral line with a control group. Consistent with previous studies, we found that cavefish orient toward flow and more frequently swim upstream at a higher flow speed. We found that these responses to flow were indistinguishable between fish with compromised and functioning lateral line systems. Rheotaxis was also unaltered by exposing fish to varying
  • H
    Gentamicin is ototoxic to all hair cells in the lateral line system.
    Hearing Research
    Jan 2010
    Hair cells of the lateral line system in fish may differ in their susceptibility to damage by aminoglycoside antibiotics. Gentamicin has been reported to damage hair cells within canal neuromasts, but not those within superficial neuromasts. This finding, based on SEM imaging, indicates a distinction in the physiology of hair cells between the two classes of neuromast. Studies concerned with the individual roles of canal and superficial neuromasts in behavior have taken advantage of this effect in an attempt to selectively disable canal neuromasts without affecting superficial neuromast function. Here we present an experimental test of the hypothesis that canal neuromasts are more vulnerable to gentamicin than superficial neuromasts. We mea
  • J
    The morphology and mechanical sensitivity of lateral line receptors in zebrafish larvae (Danio rerio)
    Journal of Experimental Biology
    Jan 2008
    The lateral line system of fish and amphibians detects water flow with receptors on the surface of the body. Although differences in the shape of these receptors, called neuromasts, are known to influence their mechanics, it is unclear how neuromast morphology affects the sensitivity of the lateral line system. We examined the functional consequences of morphological variation by measuring the dimensions of superficial neuromasts in zebrafish larvae (Danio rerio) and mathematically modeling their mechanics. These measurements used a novel morphometric technique that recorded landmarks in three dimensions at a microscopic scale. The mathematical model predicted mechanical sensitivity as the ratio of neuromast deflection to flow velocity for
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